This approach induces cerebral ischemia and monitors vascular changes in anesthetic-free mice, indicating a reliable method for microvascular analysis.
Our findings address the critical gap of microvascular-level analysis in anesthesia-confounded stroke models. The proposed approach provides a reliable and reproducible tool for the precise induction of cerebral ischemia and dynamic monitoring of vascular changes.
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Li et al. (2026) studied this question.
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