Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort | Synapse
April 22, 2026Open Access
Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort
Key Points
This study aims to evaluate the clinical efficacy of continuous apomorphine infusion in managing symptoms of multiple system atrophy.
Retrospective cohort analysis of MSA patients
Assessment of clinical response to continuous apomorphine infusion
Evaluation of tolerability in the selected patient population
Patients experienced short-term clinical benefits from continuous apomorphine infusion
Acceptable levels of tolerability observed among treated patients
Specific improvements noted in motor fluctuations and dopaminergic responsiveness
Abstract
In selected MSA patients with partial dopaminergic responsiveness and motor fluctuations, CSAI provided short-term clinical benefit with acceptable tolerability.