Do obesity and metabolic health status independently affect the risk of coronary heart disease?
The study challenges the concept of 'metabolically healthy obesity', demonstrating that both obesity and poor metabolic health independently increase the risk of coronary heart disease.
Irrespective of BMI, metabolically unhealthy individuals had higher CHD risk than their healthy counterparts. Conversely, irrespective of metabolic health, overweight and obese people had higher CHD risk than lean people. These findings challenge the concept of 'metabolically healthy obesity', encouraging population-wide strategies to tackle obesity.
Lassale et al. (Tue,) studied this question.