Computational modeling provides added value in the clinical translation of tissue-engineered heart valves by improving mechanistic understanding.
Examples of added value of computational modelling in each step of clinical translation of tissue-engineered heart valve (TEHV) from bench to bedside.In silico models can attribute to mechanistic understanding of in vitro and in vivo studies.Subfigure of TEHV performance was
“Thanks to the simulations, we can optimize the design and composition of the regenerative heart valves and develop customized implants for use in therapy.”
Visser et al. (Thu,) studied this question.