May 7, 2026Open Access

Computational modelling to reduce outcome variability in tissue-engineered heart valves

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Abstract

Examples of added value of computational modelling in each step of clinical translation of tissue-engineered heart valve (TEHV) from bench to bedside.In silico models can attribute to mechanistic understanding of in vitro and in vivo studies.Subfigure of TEHV performance was

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“Thanks to the simulations, we can optimize the design and composition of the regenerative heart valves and develop customized implants for use in therapy.”

Simon P. Hoerstrup, Professor of Regenerative Medicine, University of ZurichUniversity of Zurichauto_pipelineView source

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Authors

Valery L Visser

Polina Zaytseva

Sarah E. Motta

Journals

European Heart Journal

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Institutions

ETH Zurich

University of Zurich

Charité - Universitätsmedizin Berlin

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Computational modelling to reduce outcome variability in tissue-engineered heart valves

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Abstract

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