GWAS identifies locus associated with ICP in 13,357 Chinese pregnant women

Key Points

• The research aims to identify genetic loci associated with intrahepatic cholestasis of pregnancy (ICP) in a large cohort of Chinese pregnant women.
• Conducted a genome-wide association study (GWAS) with 13,357 participants.
• Analyzed summary statistics for ICP and total bile acids (TBA).
• Identified a significant genetic locus associated with ICP in the studied population.
• Observed variations linked to increased risk of ICP, suggesting potential biomarkers for risk assessment.