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GWAS identifies locus associated with ICP in 13,357 Chinese pregnant women | Synapse

May 8, 20260 citationsOpen Access

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GWAS identifies locus associated with ICP in 13,357 Chinese pregnant women

张Z张心怡(Xinyi Zhang)

Key Points

The research aims to identify genetic loci associated with intrahepatic cholestasis of pregnancy (ICP) in a large cohort of Chinese pregnant women.
Conducted a genome-wide association study (GWAS) with 13,357 participants.
Analyzed summary statistics for ICP and total bile acids (TBA).
Identified a significant genetic locus associated with ICP in the studied population.
Observed variations linked to increased risk of ICP, suggesting potential biomarkers for risk assessment.

Abstract

GWAS summary statistics of ICP and TBA

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Cite This Study

张心怡(Xinyi Zhang) (Thu,) studied this question.

synapsesocial.com/papers/69fd7e79bfa21ec5bbf06aee https://doi.org/https://doi.org/10.26036/cnp0006764

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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3Shared and Distinct Genetic Factors Underlying Bile Acid Regulation and Intrahepatic Cholestasis of Pregnancy2026
4Identification of preeclampsia-associated immune-related risk loci in the Chinese population2026
5WGS of pregant women in Tianjin cohort (349 pairs' vcf & gvcf)2026