A dual mode turn-on probe for H 2 O 2 sensing via fluorescence and colorimetry in live cells and serum | Synapse
May 20, 2026
A dual mode turn-on probe for H 2 O 2 sensing via fluorescence and colorimetry in live cells and serum
Key Points
The study aims to develop and evaluate a dual mode probe for accurate detection of hydrogen peroxide in live cells and serum.
Developed a probe that utilizes fluorescence and colorimetry for H2O2 detection.
Tested the probe in live cells and serum samples to assess performance.
Evaluated the sensitivity and specificity of the dual-mode approach.
The probe demonstrated a significant increase in fluorescent signal upon H2O2 exposure, indicating high sensitivity.
Colorimetric changes correlated with H2O2 concentrations, confirming the probe's effectiveness.
Successful detection in biological samples suggests potential application in physiological studies.
Abstract
Hydrogen peroxide (H 2 O 2 ), as a crucial intracellular reactive oxygen species (ROS) and secondary messenger, plays a key role in various physiological and pathological processes.