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January 1, 2026Analytical Methods

A dual mode turn-on probe for H ₂ O ₂ sensing via fluorescence and colorimetry in live cells and serum

Weitian Chen Hui Dong Siyu Wang Yitong Jiang Yujia Qian Aixin Chang Jiahui Ding Xue Yang Yanli Zhou Yintang Zhang Zhaohui Li Maotian Xu

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Key Points

The study aims to develop and evaluate a dual mode probe for accurate detection of hydrogen peroxide in live cells and serum.
Developed a probe that utilizes fluorescence and colorimetry for H2O2 detection.
Tested the probe in live cells and serum samples to assess performance.
Evaluated the sensitivity and specificity of the dual-mode approach.
The probe demonstrated a significant increase in fluorescent signal upon H2O2 exposure, indicating high sensitivity.
Colorimetric changes correlated with H2O2 concentrations, confirming the probe's effectiveness.
Successful detection in biological samples suggests potential application in physiological studies.

Implication

Examines H2O2 sensing in live cells, suggesting dual mode detection improves accuracy.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4ec0f03e14405aa99e85 https://doi.org/10.1039/d6ay00388e

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