Percutaneous aortic valve implantation significantly improved physical (from 28.5 to 41.3) and mental (from 37.8 to 48.3) quality of life scores at 5 months compared to baseline (P<0.001).
Cohort (n=30)
Does percutaneous aortic valve implantation improve quality of life and functional status in patients with aortic stenosis?
PAVI with the CoreValve prosthesis provides significant short-term improvements in both physical and mental quality of life as well as functional status in patients with aortic stenosis.
p-value: p=<0.001
AIMS: To assess the NYHA class and the quality of life (QoL) scores after percutaneous aortic valve implantation (PAVI) with the 18-Fr CoreValve prosthesis. METHODS AND RESULTS: From April 2007 until August 2008, 57 consecutive patients with aortic stenosis were evaluated for PAVI. Of these, 30 patients with successfully prosthesis implantation had more than 5-month follow-up. QoL assessment was realized with the SF-12v2 Health-Survey, a simple questionnaire designed for self-administration that provides easily interpretable scales for physical physical component summary (PCS) and mental mental component summary (MCS) health. The questionnaire was administered before and 5 months after PAVI. All 30 patients had a marked upgrading in haemodynamic and echocardiographic parameters (peak-to-peak gradient from 64 +/- 23 to 2 +/- 0.4; P 75 years, both for physical (PCS-baseline 28.5 vs. 37.9, P < 0.001) and mental scores (MCS-baseline 37.8 vs. 45.4, P < 0.001). After 5 months, a striking improvement in both scores (PCS 41.3-MCS 48.3; P < 0.001) was observed. CONCLUSION: Our preliminary results show a marked short-term improvement in functional status and physical and mental health in patients underwent PAVI.
Ussia et al. (Wed,) conducted a cohort in aortic stenosis (n=30). Percutaneous aortic valve implantation (PAVI) vs. Baseline was evaluated on NYHA class and quality of life (QoL) scores (SF-12v2) (p=<0.001). Percutaneous aortic valve implantation significantly improved physical (from 28.5 to 41.3) and mental (from 37.8 to 48.3) quality of life scores at 5 months compared to baseline (P<0.001).