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April 6, 2007Proceedings of the National Academy of SciencesOpen Access

The effect of public health measures on the 1918 influenza pandemic in U.S. cities

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Authors

MBMartin BootsmaNFNeil M. Ferguson

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Overview

Randomized trial shows public health measures impacted mortality rates during the 1918 pandemic, indicating significant city-specific variations.

Key Points

  • This research aims to examine the relationship between public health measures and mortality during the 1918 influenza pandemic in U.S. cities.
  • Analyzed per-capita excess mortality in 1918 across different U.S. cities.
  • Used an epidemic model to fit weekly mortality data from 16 cities with intervention timing information.
  • Identified correlations between the timing of interventions and mortality rates.
  • Found that early interventions significantly correlated with lower excess mortality rates.
  • Estimated that time-limited interventions reduced total mortality by 10-30%, due to delays in implementation.
  • Cities like San Francisco and St. Louis achieved reductions in transmission rates by 30-50%.

Cite This Study

Bootsma et al. (2007) studied this question.

synapsesocial.com/papers/6a1563fdb2e0231f1582697bhttps://doi.org/10.1073/pnas.0611071104
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