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April 6, 2007Proceedings of the National Academy of Sciences834 citationsOpen Access

Effect of Public Health Measures on 1918 Influenza Pandemic in U.S. Cities

The effect of public health measures on the 1918 influenza pandemic in U.S. cities

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Authors

MBMartin BootsmaNFNeil M. Ferguson

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Overview

Randomized trial shows public health measures impacted mortality rates during the 1918 pandemic, indicating significant city-specific variations.

Key Points

  • This research aims to examine the relationship between public health measures and mortality during the 1918 influenza pandemic in U.S. cities.
  • Analyzed per-capita excess mortality in 1918 across different U.S. cities.
  • Used an epidemic model to fit weekly mortality data from 16 cities with intervention timing information.
  • Identified correlations between the timing of interventions and mortality rates.
  • Found that early interventions significantly correlated with lower excess mortality rates.
  • Estimated that time-limited interventions reduced total mortality by 10-30%, due to delays in implementation.
  • Cities like San Francisco and St. Louis achieved reductions in transmission rates by 30-50%.

Cite This Study

Bootsma et al. (2007) studied this question.

synapsesocial.com/papers/6a1563fdb2e0231f1582697bhttps://doi.org/10.1073/pnas.0611071104
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