Why the study?
Does simulated microgravity (16 days of head-down-tilt bed rest) alter autonomic nervous control and increase the risk of orthostatic intolerance in human subjects?
Population
29 human subjects
Comparison
16 days of head-down-tilt bed rest vs Baseline measures before bed rest
Design
Cohort
Follow-up
16 days
Authors
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Baseline autonomic profiling may stratify post-bed rest orthostatic intolerance risk; leaves open whether targeted interventions alter outcomes in microgravity analogs.
Does simulated microgravity (16 days of head-down-tilt bed rest) alter autonomic nervous control and increase the risk of orthostatic intolerance in human subjects?
Simulated microgravity via 16 days of bed rest impairs autonomic responsiveness, and baseline autonomic profiles can predict the risk of orthostatic intolerance.
Xiao et al. (2004) studied this question.
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