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July 2, 2004Journal of Applied Physiology

Sleep restriction does not affect orthostatic tolerance in the simulated microgravity environment

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Why the study?

Does sleep restriction worsen orthostatic intolerance in healthy men exposed to simulated microgravity?

Population

19 healthy men

Comparison

Sleep-restricted protocol during 14-16 days of… vs Non-sleep restricted protocol during 14-16 days…

Design

Other

Follow-up

14-16 days

Authors

SGS. Marlene GrenonSHShelley HurwitzNSNatalie Sheynberg

Discussion

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Member takes

Overview

Sleep restriction does not worsen orthostatic intolerance after simulated microgravity in healthy men; leaves open relevance to astronauts or clinical populations.

Structured PICO

Does sleep restriction worsen orthostatic intolerance in healthy men exposed to simulated microgravity?

P
Population
19 healthy men
I
Intervention
Sleep-restricted protocol (6 hours of sleep per night) during 14-16 days of simulated microgravity (head-down tilt bed rest)
C
Comparator
Non-sleep restricted protocol (8 hours of sleep per night) during 14-16 days of simulated microgravity
O
Outcome
Orthostatic intolerance (OI) defined by development of presyncope or syncope during a tilt-stand testsurrogate

Sleep restriction does not additively worsen orthostatic intolerance or alter renal and cardioendocrine responses in healthy men exposed to simulated microgravity.

Cite This Study

Grenon et al. (2004) studied this question.

synapsesocial.com/papers/6a708c65e71d69abee08ae3fhttps://doi.org/10.1152/japplphysiol.00328.2004
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