Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
Observational
Cardiac performance and oxygenation have been studied in resting and exercising subjects with coronary artery disease. Disturbances exist in myocardial function and energetics, characterized by preservation of pressure development, but with impaired systolic ejection and failure to increase mechanical efficiency during exercise. Resultant elevation of myocardial oxygen need by impaired performance undoubtedly aggravates coronary reserve inadequacy during exercise.
Messer et al. (Sun,) conducted a observational in Coronary Artery Disease. Exercise vs. Rest was evaluated on Cardiac performance and oxygenation. Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
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