Key result
Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
Why the study?
How does exercise affect cardiac performance and oxygenation in human subjects with coronary artery disease?
Population
Human subjects with coronary artery disease
Comparison
Exercise vs Resting state
Design
Other
Authors
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May warrant caution in exercise guidance for CAD; leaves open prospective trials on efficiency modulation.
Observational
How does exercise affect cardiac performance and oxygenation in human subjects with coronary artery disease?
Exercise in patients with coronary artery disease impairs systolic ejection and mechanical efficiency, which increases myocardial oxygen demand and exacerbates coronary reserve inadequacy.
Messer et al. (1963) conducted an observational in Coronary Artery Disease. Exercise vs. Rest was evaluated on Cardiac performance and oxygenation. Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
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