Why the study?
Does exercise training improve coronary vasomotion and myocardial perfusion in patients with coronary artery disease?
Population
Patients with coronary artery disease
Design
Review
Key result
Exercise training improves myocardial perfusion in coronary artery disease by attenuating paradoxic vasoconstriction and enhancing endothelium-derived nitric oxide production.
Authors
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Supports endothelial benefits of exercise in CAD; leaves open randomized trials on perfusion outcomes.
Does exercise training improve coronary vasomotion and myocardial perfusion in patients with coronary artery disease?
Exercise training improves myocardial perfusion in CAD patients primarily by enhancing endothelial function and microcirculatory vasodilation rather than changing baseline coronary artery diameter.
Gielen et al. (2001) conducted a review in Coronary Artery Disease. Exercise training was evaluated. Exercise training improves myocardial perfusion in coronary artery disease by attenuating paradoxic vasoconstriction and enhancing endothelium-derived nitric oxide production.