Perirenal fat thickness measured with CT-scan showed a strong positive correlation with perirenal fat volume (r = 0.86 to 0.91, p <0.001), serving as a reliable estimate of perirenal fat mass.
Cross-Sectional (n=40)
Blinded endpoint evaluation
No
Does perirenal fat thickness measured by CT-scan reliably estimate perirenal fat volume in overweight and obese subjects?
Perirenal fat thickness measured by CT-scan is a simple and reliable estimate of perirenal fat volume in overweight and obese subjects.
Effect estimate: r = 0.86 to 0.91
p-value: p=<0.001
Deposition of perirenal adipose tissue has been associated with adverse renal and cardiovascular events. We compared various methods to measure perirenal adipose tissue using computerized tomography (CT)-scan and performed correlations with anthropometric measures associated with renal and cardiovascular events. Voluntary overweight and obese subjects undergoing a CT-scan for diagnostic purposes were included in the study. Perirenal adipose tissue volume, adipose tissue area of the renal sinus and perirenal fat thickness were manually measured bilaterally. The intra- and inter-observer coefficient correlations and the correlation between the diverse measures of renal adipose tissue, subcutaneous (SC-)fat and anthropometrics measures were analyzed using Pearson's correlation tests. The forty included patients (24 men, 16 women) had a mean age of 57.6 ± 18.1 years and a mean body mass index of 28.9 ± 2.9 kg/m2. Despite comparable waist circumference, women had a greater SC-fat thickness compared to men, and therefore a smaller amount of visceral fat, as well as smaller perirenal fat volumes. Perirenal fat thickness was better correlated with perirenal fat volume than adipose area of the renal sinus (p <0.02). The adipose area of the renal sinus did not correlate with any anthropometric measures. In women, perirenal fat volume and thickness showed a negative correlation with SC-fat thickness and no correlation with waist circumference. In men, perirenal fat volume and thickness showed a positive correlation with waist circumference and no correlation with subcutaneous fat thickness. In conclusion, perirenal fat thickness measured with CT-scan at the level of the renal veins is a simple and reliable estimate of perirenal fat volume, that correlated negatively with SC-fat in women and positively with waist circumference in men. The adipose area of the renal sinus did not correlate with any anthropometric measure.
Favrè et al. (2017) conducted a cross-sectional in Overweight and obesity (n=40). Perirenal fat thickness measured with CT-scan was evaluated on Correlation between perirenal fat thickness and perirenal fat volume (r = 0.86 to 0.91, p=<0.001). Perirenal fat thickness measured with CT-scan showed a strong positive correlation with perirenal fat volume (r = 0.86 to 0.91, p <0.001), serving as a reliable estimate of perirenal fat mass.