Scripps Research Institute

Recent papers from Scripps Research Institute

1. FlAsH-ID enables live-cell photoproximity labeling with a short peptide tagNature Chemical Biology · 2026
2. HIV broadly neutralizing antibody precursor maturation induced by mRNA vaccination in nonhuman primates2026
3. A Hybrid Fluorescence-Optoelectronic Nanoscale Sensor for the Early Diagnosis of Tau PathologyACS Sensors · 2026
4. Maladaptive state allocation: an orexin-based framework linking sleep disturbance, chronic pain, and substance use disorderFrontiers in Neuroscience · 2026
5. Rgs7bp-Deficient Mice Show Increased Ethanol Drinking and Quinine Resistance with Altered Negative Affective Behaviors in Intermittent Access to Ethanol Paradigms2026
6. Structural basis of hypervariable region 1 dynamics on HCV envelope glycoproteins in immune evasionProceedings of the National Academy of Sciences · 2026
7. Redox-Neutral Copper-Catalyzed Syntheses of Allylic and Benzo-Fused Secondary LactamsOrganic Letters · 2026
8. Amyloid nomenclature 2026: update, novel proteins, and discussion of intracellular aggregates and toxicity. Recommendations by the International Society of Amyloidosis Nomenclature CommitteeAmyloid · 2026
9. WASH orchestrates phagosomal maturation and bacterial killing in neutrophils through syntaxin 19-mediated lysosomal fusionNature Communications · 2026
10. Sex-at-birth, innate immunity, and HIV reservoir selectionCurrent Opinion in HIV and AIDS · 2026
11. Fast and accurate resolution of ecDNA sequence using Cycle-ExtractorGenome Research · 2026
12. The origin of the MV Hondius Andes outbreak2026
13. Integrated transcriptomic and epigenomic profiling of human cartilage reveals coordinated changes in fibronectin expression, splicing, and receptor signaling during osteoarthritis progression2026
14. Autophagy activator AA-20 engages CDK5 to promote lipophagy and improve neurodegeneration-associated phenotypes2026
15. Dairy cattle movement networks govern the spread and persistence of H5N1 B3.13 in the United States2026
16. Antibodies to distinct epitopes on MPXV enveloped virion provide additive and complete protectionScience Immunology · 2026
17. Single-nucleus multiome profiling reveals osteocyte-centered remodeling of human subchondral bone across osteoarthritis severity2026
18. Metformin at the Time of COVID‐19 Infection and Risk of Long COVID: A Target Trial Emulation StudyJournal of Medical Virology · 2026
19. Survey of the human proteostasis network: the ubiquitin-proteasome systemAutophagy · 2026
20. Targeted CPSF6 recoding reveals global fitness advantages of SPAD integration targeting and cell type-specific roles for capsid binding in HIV-1 DNA synthesis and nuclear importmBio · 2026