The Wistar Institute

Recent papers from The Wistar Institute

1. Lowering the Barr: Rethinking Causality in Complex Autoimmunity Through Epstein-Barr Virus in Multiple SclerosisNeurology Neuroimmunology & Neuroinflammation · 2026
2. Loss of CDKN2A remodels Golgi morphology to create a lipid peroxidation vulnerability2026
3. Natural killer cell engineering strategies for HIV cure and reservoir eliminationCurrent Opinion in HIV and AIDS · 2026
4. A practical workflow for isolation and low-input multi-omic and functional profiling of neutrophils from tumor tissueFrontiers in Immunology · 2026
5. DoAggregate: a pipeline for aggregation testing for rare-variant on a gene and pathway level2026
6. NAD Metabolism Drives CTCF-Cohesin Chromatin Regulation in EBV-Transformed B-Cells2026
7. Stem cells for hepatic regeneration: Evaluating mechanisms, sources, and clinical outcomesBiochemistry and Biophysics Reports · 2026
8. TEDEdb: A multicohort analysis and resource for transposable element differential expression in cancerProceedings of the National Academy of Sciences · 2026
9. The pan-African natural products library compounds oleanolic acid, poinsettifolin B, and rhuschalcone III disrupt SARS-CoV-2 spike-host ACE2 interactions and SARS-CoV-2 replicationBMC Pharmacology and Toxicology · 2026
10. Real-time exploration of the billion-scale human repertoire for precursor frequency analysis and rational antibody designFrontiers in Immunology · 2026
11. FDXR upregulation by p63/p73 is a prognostic and therapeutic marker of adult T-cell leukemia/lymphomaEMBO Molecular Medicine · 2026
12. Aberrant erythrocyte rigidity in JAK2 V617F myeloproliferative neoplasms underlies concurrent thrombosis and hemorrhageScience Translational Medicine · 2026
13. Immune Subtypes and Survival in Patients with Primary GliomaNeuro-Oncology Advances · 2026
14. Myeloid-derived suppressor cells in hematologic malignancies: A current state of the fieldThe Journal of Immunology · 2026
15. Dopamine-induced mitochondrial dysfunction activates cGAS-sTING to drive IL-6 secretion in macrophagesCell Reports · 2026
16. Activation of cytosolic DNA sensing in NCM460 intestinal epithelial cells induces antiviral factors that restrict HIV infection in macrophagesFrontiers in Immunology · 2026
17. ERVmancer: a phylogeny-guided framework for decoding human endogenous retrovirus regulatory mechanisms in health and diseaseGenome biology · 2026
18. NMR‐Guided Fragment Screening Identifies Privileged Noncanonical Amino Acids for mRNA DisplayChemBioChem · 2026
19. Targeting hypoxia-driven histone lactylation in myeloid cells synergizes with CD137 agonism to expand effector-like exhausted CD8+ T cells in glioblastomaNeuro-Oncology · 2026
20. The role of germline transposable element insertions in pediatric cancer predispositionCancer Research Communications · 2026