Tokyo Metropolitan Institute of Medical Science

Recent papers from Tokyo Metropolitan Institute of Medical Science

1. Aging remodels the suprachiasmatic nucleus and weakens ultradian rhythms and activity–temperature couplingCommunications Biology · 2026
2. Cryo-EM structures of human α-synuclein filaments reveal the molecular basis of PET tracer ACI-12589 recognition2026
3. Metformin Induces Persistent DNMT1-Associated DNA–Protein Cross-Links under Glucose DeprivationChemical Research in Toxicology · 2026
4. Where the clone is selected: stage-specific selection from hematopoietic stem cells to plaque macrophages in clonal hematopoiesisFrontiers in Cardiovascular Medicine · 2026
5. Developmental perturbation of Purkinje cell function induces male-biased core and associated autism spectrum disorder–like phenotypes in adulthood2026
6. Oligodendrocytes may provide the extra density of α-synuclein filaments from multiple system atrophy2026
7. Patient and public involvement in amyotrophic lateral sclerosis research in Japan: a survey through nationally advertised ALS Café events and a pilot advocacy training programResearch Involvement and Engagement · 2026
8. Antimicrobial peptides derived from Nemuri induce ribosomal condensation to inhibit translationNature Communications · 2026
9. Acute Loss of TrkB Signaling Impairs the Survival of Mature Retinal Ganglion Cells and Retinal FunctionInvestigative Ophthalmology & Visual Science · 2026
10. Systematic review and meta-analysis of cognitive behavioral therapy for insomnia as a suicide prevention strategyNature Mental Health · 2026
11. Jet-injected combinational adjuvants potentiate naked mRNA vaccines for protection against respiratory viral infections in miceJournal of Clinical Investigation · 2026
12. Fibroblast-Derived PLA2G12A Amplifies Mast Cell Activation Through Extracellular Phospholipid RemodelingCells · 2026
13. Non‐Invasive Visualization of Cells Expressing Unmodified Target mRNA Using a Programmable RNA ‐Mediated BiFC PlatformGenes to Cells · 2026
14. Probable sudden unexpected death in epilepsy in chronic febrile infection‐related epilepsy syndrome survivors: Silent threat after the stormEpileptic Disorders · 2026
15. Exogenous pyruvate protects IMS32 Schwann cells from impairing the maturation process under hyperglycemiaThe Journal of Physiological Sciences · 2026
16. Prion-like transmission of human tau strains in the mouse brainNature · 2026
17. Most Early‐Born Subplate Neurons Persist as Layer 6b Neurons in the Adult Mouse NeocortexThe Journal of Comparative Neurology · 2026
18. Inhibition of PDGF signal suppresses the fibrotic scar formation and promotes axonal regeneration in a mouse nigrostriatal lesion modelAJP Cell Physiology · 2026
19. Combining Antiviral Therapy with Cancer Treatment in HBV-associated HCC: A Translational ApproachVirus Research · 2026
20. Multi-omics atlas of chronic exerciseCell · 2026