Genome Institute of Singapore

Recent papers from Genome Institute of Singapore

1. An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI ActivationAllergy · 2026
2. Pre‐emptive pharmacogenomics testing in clinical practice: A pilot implementation in SingaporeBritish Journal of Clinical Pharmacology · 2026
3. Integration and annotation of spatial multi-omic data with DIRACNature Methods · 2026
4. Comparative Age-Period-Cohort Analysis Reveals Divergent Temporal Trajectories of Breast and Colorectal Cancer Among Women in SingaporeCancers · 2026
5. Polygenic and classical risk integration reshapes breast cancer screening recommendations in 9,761 Asian womenBMC Medicine · 2026
6. A clinical multimodal vision language foundation model with fine-grain explainabilityNature Medicine · 2026
7. Integrative Genomic Analyses Identify Collagen Type XXI Alpha 1 Chain and ENPEP‐Fibroblast Growth Factor 5 Regulatory Pathways for Blood Pressure Variation in East Asian PeopleJournal of the American Heart Association · 2026
8. An environmentally regulated dichotomy in cell lineages of the rootNature · 2026
9. Implementing reproductive carrier screening to include diverse Asian populations: insights from SingaporeBMC Medicine · 2026
10. Differences in Somatic Mutations Between Early-Onset and Late-Onset Colorectal Cancer: A Systematic Review and Meta-AnalysisCancers · 2026
11. Epigenome-wide association study in Asian cohort identifies novel DNA methylation markers for carotid intima-media thicknessClinical Epigenetics · 2026
12. scURL: Uncertainty-Sharpened Representation Learning for Single-cell Multi-omics ClusteringBioinformatics · 2026
13. Targeting chondroitin synthase 1 attenuates hyperplastic arterial remodeling via gene therapyCommunications Biology · 2026
14. Genomic and transcriptomic landscape of spread through air spaces in stage 1 lung adenocarcinomaBritish Journal of Cancer · 2026
15. Identification of novel paracrine therapeutic targets in peritoneal metastases through integrative proteotranscriptomic analysis of ascitesMolecular Cancer · 2026
16. Contribution of copy number variants to schizophrenia in East Asian populationsNature Genetics · 2026
17. Copper and iron engage distinct metabolic programs for cellular survivalGeroScience · 2026
18. Telomere variant sequences encode the genetic blueprint for allele-specific telomere lengthNature Communications · 2026
19. Hunting for microsatellite instability in long-read data with OwlPLoS Computational Biology · 2026
20. “Swab-and-Stain” Nanoparticle Assay for Detection of PBP2a-Expressing Methicillin-Resistant Staphylococcus aureus Toward Point-of-Need Environmental SurveillanceMicroorganisms · 2026