Genomics Research Center, Academia Sinica

Recent papers from Genomics Research Center, Academia Sinica

1. An LHX2-DACH1 regulatory innovation drives basal progenitor expansion in the primate neocortexScience Advances · 2026
2. Repurposing of abemaciclib to overcome C797S-mediated osimertinib resistance in EGFR-mutant lung adenocarcinomaJournal of Biomedical Science · 2026
3. HSPB8 regulates CTP synthase filaments to couple nucleotide metabolism and autophagy in tumorsCell Death Discovery · 2026
4. CircaVal: a gene-centric multi-omics platform for exploring circadian regulatory featuresNucleic Acids Research · 2026
5. High-Throughput Virome Surveillance Reveals Emerging Viral Threats to Cucumber Production in TaiwanViruses · 2026
6. Outcomes associated with surgical ligation versus medical treatment for patent ductus arteriosus in extremely preterm infantsScientific Reports · 2026
7. Association between cervical human papillomavirus infection and bladder cancer risk: A community-based cohort studyJournal of Infection and Public Health · 2026
8. Integrated microRNA–protein plasma biomarkers improve discrimination of multiple system atrophy from Parkinson’s diseasenpj Parkinson s Disease · 2026
9. Hepatocellular carcinoma surveillance in Europe: challenges and lessons from global practiceThe Lancet Regional Health - Europe · 2026
10. Structural Characterization and Engineering of a GH134 β-Mannanase from Aspergillus nidulans for Enhancement of Activity and StabilityJournal of Agricultural and Food Chemistry · 2026
11. Leucine-rich repeat neuronal protein 1 as a novel biomarker of breast cancer stem cells and poor prognosis in patients with breast cancerStem Cell Research & Therapy · 2026
12. Unraveling the immune landscape and molecular signatures of antibody-dependent cellular cytotoxicity in SARS-CoV-2 clearanceCommunications Biology · 2026
13. Recent advances in the chemical synthesis of GlycosaminoglycansCurrent Opinion in Chemical Biology · 2026
14. Increased CCR5 expression in lymphoma cells and M2 macrophages is associated with poor prognosis in primary intestinal diffuse large B‐cell lymphomaThe Journal of Pathology Clinical Research · 2026
15. Integrative analysis of bulk, single-cell, and spatial transcriptomes reveals a clinically relevant transcriptional program from hepatocellular carcinoma to pan-cancerDiscover Oncology · 2026
16. Humoral responses in skin inflammation resulted from altered expression of epidermal Blimp-1 2308147The Journal of Immunology · 2026
17. Core elements play distinct roles in promoter birth and transcriptional regulationNature Communications · 2026
18. Oncogenic PIK3CA mutation enhances tumor immunogenicity through the IRF1–NLRC5–MHC-I axis in urothelial carcinomaJournal for ImmunoTherapy of Cancer · 2026
19. Evolving patterns of childhood myopia in Taiwan: Effects of urbanization, digitalization, and outdoor activity policiesTaiwan Journal of Ophthalmology · 2026
20. Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71Science Advances · 2026