The Gurdon Institute

Recent papers from The Gurdon Institute

1. Scalable variant-to-function screens using prime editing perturb-seq2026
2. In preprints – pushing the limits of morphogen scaling in limb regenerationDevelopment · 2026
3. FuChi is a cell cycle biosensor for tracking cell cycle dynamics during avian developmentPLoS Biology · 2026
4. Safety of combining radiation therapy and antibody-drug conjugates in patients with breast cancer: a systematic review and meta-analysisRadiotherapy and Oncology · 2026
5. Cancer treatment alters mutant selection in normal esophagusNature Genetics · 2026
6. Protocol for fixation and staining of Drosophila melanogaster embryos optimized for DNA-PAINT nanoscopy of adherens junction proteinsSTAR Protocols · 2026
7. Integrating historical sources with climate simulations: Temperature and precipitation anomalies in southern Italy (1000–1800 CE)Quaternary Science Reviews · 2026
8. Extracellular-matrix mediated stresses spatially bias myoblast fusion and myotube growthNature Communications · 2026
9. Programmable multifunctional microrobots for synergistic cuproptosis-immunotherapyNational Science Review · 2026
10. Targeting epigenetic regulators induces transcription-replication conflicts to overcome ATR inhibitor resistanceNucleic Acids Research · 2026
11. Rapid discovery of monoclonal antibodies via high-throughput single BCR affinity sequencingNucleic Acids Research · 2026
12. NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy modeliScience · 2026
13. Conserved and divergent DNA methylation features of extraembryonic tissues between human, mouse and chickenBMC Genomics · 2026
14. AMPK tunes reproductive gene expression and small RNA homeostasis to mediate timely germ cell developmentNucleic Acids Research · 2026
15. Radical diffusion, not lifetime, determines the range of Peroxidase-based proximity labellingJournal of Cell Science · 2026
16. NELFA supports naïve pluripotency and drives 8C-like state in human embryonic stem cells.2026
17. Early fibrotic niches establish tumour-permissive microenvironmentsNature · 2026
18. Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitorseLife · 2026
19. RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress responseMolecular Cell · 2026
20. Harnessing glucocorticoid receptor antagonism to enhance the efficacy of cardiac regenerative growth factors and cytokinesNature Cardiovascular Research · 2026