Institute for Neurodegenerative Disorders

Recent papers from Institute for Neurodegenerative Disorders

1. Path to Prevention Platform Trial in Early-Stage Neuronal Alpha-Synuclein Disease: Study Design2026
2. Statistical design of Path to Prevention platform trial in early neuronal alpha-synuclein disease2026
3. Rates of Phenoconversion and Progression to Functionally Meaningful Impairment in NSD Stage 2B Participants: PPMI Cohort2026
4. Early functional neuroimaging alterations in pTau217 biomarker-positive older adultsFrontiers in Aging Neuroscience · 2026
5. Strategies to establish a biologically defined Parkinson′s disease cohort prior to the onset of clinically significant motor symptoms2026
6. Factor structure of the Community Screening Interview for Dementia (CSI-D) among Zambian adultsnpj Dementia · 2026
7. Blood-Based Biomarkers as Predictors of All-Cause DementiaNeurology · 2026
8. Consistency of Serial Cerebrospinal Fluid α‐Synuclein Seed Amplification Assay Results in the Parkinson's Precision Medicine InitiativeMovement Disorders · 2026
9. An AI-Enabled Translational Drug Discovery Framework for NALCN Channelopathy: From High-Throughput Screening to Therapeutic Candidate2026
10. Synaptic Function and Modulation in Health and DiseaseBiomedicines · 2026
11. Development of Organocatalytic Switches of OGG1 that Protect Mitochondria under Oxidative StressJournal of Medicinal Chemistry · 2026
12. Differential proteostasis imbalance and the molecular basis of distinct synucleinopathies and tauopathiesPhilosophical Transactions of the Royal Society B Biological Sciences · 2026
13. Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular AgeArteriosclerosis Thrombosis and Vascular Biology · 2026
14. Ubiquitin Proteasome System BTB-Adaptor Protein Insomniac Modifies Seizure Severity and Response to the Ketogenic Diet in a Drosophila Model of Mitochondrial EncephalomyopathyGenes · 2026
15. Minding the gates: dual cell-autonomous and non-cell-autonomous mechanisms of TBK1 in ALS/FTDFrontiers in Neuroscience · 2026
16. Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across AncestriesNeurology Genetics · 2026
17. Amyloid-beta-targeting monoclonal antibodies in early Alzheimer’s disease: a cochrane review summary and appraisal for the neurological communityNeurological Sciences · 2026
18. Fatty acid nitroalkene inhibition of LRRK2 hyperactivation and induction of neuroprotection in a model of Parkinson’s diseasenpj Parkinson s Disease · 2026
19. The effects of physical and sensory activities on motor and cognitive functions in the aging brain: a reviewThe Journals of Gerontology Series A · 2026
20. Regulators of interferon-responsive microglia uncovered by Genome-wide CRISPRi screeningnpj Dementia · 2026