Oxford University Clinical Research Unit

Recent papers from Oxford University Clinical Research Unit

1. An explainable machine learning pipeline using XGBoost and SHAP to identify factors associated with tuberculosis treatment adherence in a district health centerDiscover Public Health · 2026
2. Cross-reactive T cell immunity against novel coronaviruses with pandemic potential, predictable from spike sequence conservationClinical & Experimental Immunology · 2026
3. Early best available antibiotic therapy for multidrug-resistant gram-negative bloodstream infections: a target trial emulationEClinicalMedicine · 2026
4. Case Report: Coombs-Negative Hemolytic Anemia as the Initial Manifestation of Wilson Disease in an Adolescent Female: A Case ReportWellcome Open Research · 2026
5. Genomic diversity and phenotypic heterogeneity of Klebsiella pneumoniae isolates causing bloodstream infection in an infectious disease hospital in Ho Chi Minh City, Vietnam2026
6. A white-light endoscopy-based mixed-effects nomogram for predicting small colorectal polyp neoplasia in resource-limited settingsPolskie Archiwum Medycyny Wewnętrznej · 2026
7. The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023The Lancet · 2025
8. Magnesium sulphate for treatment of severe tetanus: a randomised controlled trialThe Lancet · 2006
9. Impact of temperature on patient-derived dengue virus breakthrough infections in wMel-infected Aedes aegyptiPLoS neglected tropical diseases · 2026
10. Strengthening sustainable clinical trial models for greater health impact: Expert discussion from the Annual Wellcome Major International Programme Regional Meeting 2024.Wellcome Open Research · 2026
11. Modelling Simian malaria disease dynamics in Southern Thailand to inform surveillance strategies for emerging zoonotic diseases.Wellcome Open Research · 2026
12. Virological and epidemiological investigations of a severe hand foot and mouth disease outbreak, Vietnam, 2023PLoS neglected tropical diseases · 2026
13. Beyond rescue: building a resilient health system after Nepal's 2026 floodThe Lancet · 2026
14. Mapping the evolutionary path towards multi-drug resistance in the pandemic Escherichia coli ST131 lineageMicrobial Genomics · 2026
15. Functional antibody responses and protection against symptomatic dengueCommunications Medicine · 2026
16. Balancing altruism, risk and ethics: Vietnamese students’ views on human challenge studiesPLoS ONE · 2026
17. A target product profile and roadmap for Japanese encephalitis diagnostics in endemic areas in the context of other flavivirusesPLoS neglected tropical diseases · 2026
18. Risk of hepatitis B reactivation following corticosteroids for tuberculous meningitisOpen Forum Infectious Diseases · 2026
19. Accelerating the clinical development of treatments for dengue: WHO dengue therapeutics landscape analysis and target product profilesThe Lancet Microbe · 2026
20. Zoonotic disease risk perceptions associated with commercial wildlife activities in Southeast Asia: A scoping reviewCABI One Health · 2026