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High-dose corticosteroids may cause reactivation or relapse of hepatitis B virus infection. We investigated the virologic and clinical consequences of 6-8 weeks dexamethasone in hepatitis B virus infected/exposed/unexposed HIV-negative adults with tuberculous meningitis enrolled into a placebo-controlled trial. Dexamethasone was not associated with viral reactivation or increased liver injury.
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Donovan et al. (2026) studied this question.
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