Institut de Génétique Humaine

Recent papers from Institut de Génétique Humaine

1. The rapid delivery of RNase H variants reveals distinct classes of RNA:DNA hybridsThe EMBO Journal · 2026
2. DMRT1 is required at two steps of ovarian differentiation in rabbitsScience Advances · 2026
3. Mediator-associated proteins and the small RNA–guided Polycomb repressive complex enhance cryptic transcription for transposon exclusionProceedings of the National Academy of Sciences · 2026
4. Evaluating the roles of testosterone and sex-linked genes in territorial aggression of sex-reversed XY females in the African pygmy mousePeer Community Journal · 2026
5. Hippo/YAP1 signaling regulates the Oligodendrocyte–Astrocyte fate switch and ependymal gene expression in adult spinal cord stem cellsCellular and Molecular Life Sciences · 2026
6. Extensive variation in virus-induced patterns of transposable element transcripts in DrosophilaJournal of Virology · 2026
7. Divergent proteomic landscapes and functional requirements for telomere maintenance in type I and type II ALT mESCsMolecules and Cells · 2026
8. The elongation of Mest transcript into MestXL sustains, but does not initiate, the maternal allele bias of its convergent gene Copg2 during neurogenesisNature Communications · 2026
9. The rapid delivery of RNase H variants reveals distinct classes of RNA:DNA hybrids2026
10. A scaffolding element rewires local 3D chromatin architecture during differentiationNature Communications · 2026
11. Characterization of immunoglobulin loci in Pongo abelii and Pongo pygmaeus : Insights from multi-genome annotation and IMGT-based curationNAR Genomics and Bioinformatics · 2026
12. Inflammatory bone marrow microenvironment impairs the therapeutic effect of daratumumab-lenalidomide in multiple myelomaBiomarker Research · 2026
13. IMGT-NC Engineered Variants of INN Therapeutic IG or Antibodies and Related IgSF Proteins (TR, FPIA and CPCA): Bridging Sequences, Structures and Functions for AIBiomolecules · 2026
14. CD200 is a potent new growth factor in Multiple Myeloma dependent on IGF1 receptor signalingTranslational Oncology · 2026
15. Loss of SUMOylation drives aberrant PRC1 clustering and 3D genome rewiring independent of H3K27me3Nucleic Acids Research · 2026
16. Modification of the Transcription Factor FOXL2 at Serines 101 and 107 Disables DNA Binding, Leads to Nucleolar Relocalization, and Rewires Granulosa‐Cell ProgramsThe FASEB Journal · 2026
17. Multi-omics characterization of IDH-mutant astrocytoma-derived cell lines reveals NOTCH-regulated plastic quiescent astrocyte-like state and insights into progressionActa Neuropathologica Communications · 2026
18. BioImageIT: A novel python‐based architecture for reproducible bio‐image workflowsJournal of Microscopy · 2026
19. Single-nuclei UPR profiling by flow cytometry reveals bortezomib resistance mechanisms in multiple myelomaEMBO Molecular Medicine · 2026
20. Monitoring microscope performance in an imaging facility using OMERO-metrics2026