Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques

Recent papers from Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques

1. Striatofugal balance and beneficial effects of facilitating nucleus accumbens mGlu4 receptor activity in the Fmr1-/- mouse model of Fragile X SyndromePharmacological Research · 2026
2. Structural and functional divergence of cancer hotspot mutations in CREBBPProceedings of the National Academy of Sciences · 2026
3. An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activationScience Immunology · 2026
4. The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor developmentCell Death and Disease · 2026
5. Ultrafast versus Continuous-Wave Plasmonics: How Heat and Hot Electrons Drive PolymerizationACS Applied Materials & Interfaces · 2026
6. Erlotinib and Leflunomide Disrupt 6‐Formylindolo[3,2‐ b ]Carbazole Metabolism and Sensitize Keratinocytes to UVA Radiation‐Induced ApoptosisPhotodermatology Photoimmunology & Photomedicine · 2026
7. Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐AlcoholsChemistryEurope · 2026
8. Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 induced pluripotent stem cell-derived neural cellsDisease Models & Mechanisms · 2026
9. Planar Chirality Directs Enantiospecific Diastereoselectivity in Isocyanide-Based Multicomponent ReactionsACS Organic & Inorganic Au · 2026
10. Dysregulated dsRNA sensor signaling and viral infection during onset of pediatric autoimmune interferonopathy2026
11. Nutritional potential, antinutritional factors, mineral bioavailability and pesticide content of seven herbal spices from Burkina Faso gastronomyFrontiers in Food Science and Technology · 2026
12. Topological rules and anomalies in intramolecular G-quadruplex folding: a comprehensive studyNucleic Acids Research · 2026
13. Unlocking the Functionalization and Reactivity of Ethylene Bridges in [2.2]Paracyclophanes: Strategies and ChallengesEuropean Journal of Organic Chemistry · 2026
14. Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s DiseaseACS Chemical Neuroscience · 2026
15. Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity ChromatographyACS Pharmacology & Translational Science · 2026
16. Engineering Bisubstrates to Target m ⁶ Am RNA Methyltransferases: Synthesis and Computational StudiesChemistry - A European Journal · 2026
17. Plasmon-Mediated Functionalization of Gold Nanoparticles by Aryl Diazonium Salts for Controlled Surface Patterning: Impact of Annealing on Roughness and RegioselectivityACS Applied Nano Materials · 2026
18. Iron-Catalyzed Site-Selective γ-C(sp ³ )-H Azidation of Hydroxylamine DerivativesThe Journal of Organic Chemistry · 2026
19. Reaction of an Iron(II) amido complex with thiophenol and Benzeneselenol: Characterization of the adducts and catalytic oxidation by dioxygen.Inorganica Chimica Acta · 2026
20. Intrinsically disordered SERBP1 regulates translation through topology-driven G-quadruplex recognition2026