Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

Recent papers from Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

1. Fall-risk in genetic variable cytochrome P450 enzymes and exposure to anticholinergic drugs – a pilot-analysis from the ADRED-studyPharmacogenomics · 2026
2. Physiologically based pharmacokinetic modeling as a translational tool in forensic toxicology: from pig to human synthetic cannabinoid toxicokinetics using 5F-Cumyl-P7AICA and its major metabolite as a case studyArchives of Toxicology · 2026
3. Enrichment and spatial convergence of transthyretin, OxPL, plasminogen and Lp(a) in calcific aortic valve stenosisEuropean Heart Journal · 2026
4. A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver diseaseNature Genetics · 2026
5. Reduced Peritoneal NRF2 Immunoreactivity in Encapsulating Peritoneal Sclerosis and Its Implications for Redox HomeostasisAntioxidants · 2026
6. Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by AcetaminophenAdvanced Science · 2026
7. The Burden of Disease of Medication Errors: Analysis in ADR Caused Emergency VisitsPharmacoepidemiology · 2026
8. Ferroptosis blockade: beyond preservation to active graft therapySignal Transduction and Targeted Therapy · 2026
9. Chiral Separation of Tacrine-Based Metabolites: A Step Towards a Safe, Highly Active DrugJournal of Analysis and Testing · 2026
10. The FAP × CD3 bispecific antibody OMTX305 induces T cell–mediated antitumor effects in patient-derived ex vivo models of solid tumorsScience Advances · 2026
11. Allogeneic stem cell transplantation after myeloablative conditioning with fludarabine, thiotepa, and cyclophosphamide in relapsed or refractory aggressive B-cell and T-cell lymphomas: results of the prospective ASTRAL studyHaematologica · 2026
12. Protocol for extended-plex immunofluorescence staining of FFPE tissues using a sequential bleach-and-stain approachSTAR Protocols · 2026
13. N-Acetylcysteine Protects HPMCs from High-Glucose-Induced Oxidative DNA DamageAntioxidants · 2026
14. Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert PanelClinical Pharmacology & Therapeutics · 2026
15. The challenge of patient recruitment into early phase clinical trials: Is time-effective academic translational research feasible? Lessons from a phase I/II trial in patients with B-cell deficienciesFrontiers in Medicine · 2026
16. Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug ExposureClinical Pharmacology & Therapeutics · 2026
17. GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathwaysCell chemical biology · 2026
18. Cost-effectiveness of a telephone health coaching and remote exercise monitoring for peripheral artery disease (TeGeCoach)American Journal of Preventive Cardiology · 2026
19. Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitisBritish Journal of Pharmacology · 2026
20. Response to “Refining FIB-4-based risk stratification in adverse drug reactions”European Journal of Clinical Pharmacology · 2026