Key result
High liver fibrosis risk (FIB-4 score ≥2.67) was significantly associated with serious adverse drug reactions (OR 2.27) and poor discharge status (OR 3.22) in patients admitted to emergency care.
Why the study?
Does an elevated FIB-4 score predict serious outcomes in patients admitted with adverse drug reactions?
Does an elevated FIB-4 score predict serious outcomes in patients admitted with adverse drug reactions?
Elevated FIB-4 score serves as a pragmatic clinical marker associated with serious outcomes in patients admitted with adverse drug reactions, independent of comorbidity burden.
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Henze et al. (2026) conducted a letter in Adverse drug reactions (n=1,087). High liver fibrosis risk (FIB-4 score ≥2.67) vs. Low liver fibrosis risk was evaluated on Serious adverse drug reaction (stay in ICU, life-threatening ADR, or death) (OR 2.27, 95% CI 1.48-3.48). High liver fibrosis risk (FIB-4 score ≥2.67) was significantly associated with serious adverse drug reactions (OR 2.27) and poor discharge status (OR 3.22) in patients admitted to emergency care.
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