Institute for Research in Immunology and Cancer

Recent papers from Institute for Research in Immunology and Cancer

1. Chemokine and opioid peptide scavenging through constitutive and ligand-induced release of ACKR3-bearing extracellular vesiclesNature Communications · 2026
2. ACF7 promotes spontaneous metastasis in HER2-driven breast cancer through cytoskeletal coordination2026
3. Chemical genetic screens combine target dependence with efficacy: discovery of a MAP3K1 degrader (HBC-8) with anticancer activitiesMolecular Biomedicine · 2026
4. A genetic platform to deconvolve efficacy and toxicity reveals the on-target effects of CDK11 inhibition in vivoNature Communications · 2026
5. Conserved Core but Divergent Biochemical Features of RAS-MAPK Signalling in C. elegansCommunications Biology · 2026
6. Cell‐Free DNA as a Biomarker of Cell Death and Treatment Response for On‐Chip Three‐Dimensional Tumor ModelsAdvanced Healthcare Materials · 2026
7. Impact of PCSK5, cargoed by apoptotic endothelial exosome-like vesicles, on vascular repair and angiogenesisCell Death and Disease · 2026
8. Optimized Epitope-Flanking Sequences Enhance Antigen Presentation and T-Cell Responses Following mRNA VaccinationCells · 2026
9. Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficitsBrain · 2026
10. Evaluation of a Novel Fluorescent Marker for Continuous Live Imaging of Preimplantation EmbryosJournal of Developmental Biology · 2026
11. The structure of the dopamine D 3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacologyScience Advances · 2026
12. BiDRA: Bayesian Inference as a Robust Alternative to Non-Linear Regres-sion for Dose-Response Efficiency Metrics AssessmentBioinformatics Advances · 2026
13. Modeling KRAS mutations in KMT2A::MLLT3 acute myeloid leukemia promotes leukemic progression and transcriptional rewiringLeukemia · 2026
14. Ptpn2 limits plasma cell fate and antiviral immunity by integrating B cell receptor and IFN-γ signals in B cellsScience Advances · 2026
15. Invariant chain controls HLA-DQ folding and shapes the HLA class II proxiomeThe Journal of Immunology · 2026
16. Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBCCell Reports Medicine · 2026
17. A distinctive PDZ:β-hairpin interaction mediates AFDN complex with SCRIB and promotes binding to KRASBiochemical Journal · 2026
18. Modeling the Sensitivity of Large-Scale Virtual Screening to Scoring Function Accuracy, Artifacts, and Library CompositionJournal of Chemical Information and Modeling · 2026
19. Expanding the C. elegans toolkit with gonad explantsDevelopment · 2026
20. Neoadjuvant stereotactic body radiation therapy with durvalumab and oleclumab in ER+HER2− breast cancer: a randomized phase 2 trialNature Medicine · 2026