NIHR Nottingham Digestive Diseases Biomedical Research Unit

Recent papers from NIHR Nottingham Digestive Diseases Biomedical Research Unit

1. Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026Gastric Cancer · 2026
2. The effect of pectin supplementation on geriatric individuals with frailty: a randomised placebo-controlled dietary intervention studyGeroScience · 2026
3. Re‐evaluating variability of circulating miR‐122 in healthy volunteers: Implications for biomarker qualification in drug‐induced liver injuryBritish Journal of Clinical Pharmacology · 2026
4. Clinical Trial: Randomised Placebo‐Controlled Trial of Methylcellulose and Psyllium Gels on Inulin‐Induced Colonic GasAlimentary Pharmacology & Therapeutics · 2026
5. Tissue and blood-based predictive biomarkers in hepatocellular carcinoma immunotherapy: synthesis of 2023–2026 evidence and a proposed clinical integration frameworkFrontiers in Oncology · 2026
6. Utility of monocyte-derived cells to investigate immune-mediated drug-induced liver injuryToxicology Letters · 2026
7. Cardiorespiratory fitness is inversely associated with non-invasive markers of hepatic steatosis and fibrosis: a cross-sectional study of 39,197 UK adultsBMC Gastroenterology · 2026
8. Quantitative MRI to Assess Portal Pressure in Patients With Liver Disease: Validation at 3 TNMR in Biomedicine · 2026
9. Prospective validation of imaging and serum diagnostic biomarkers of steatohepatitis and fibrosis in MASLD: the LITMUS Imaging StudyNature Medicine · 2026
10. Diagnostic routes for hepatocellular carcinoma in the UK: a multicentre evaluationFrontline Gastroenterology · 2026
11. Hepatocellular carcinoma ultrasound surveillance adherence and outcomes in the UK: a multicentre retrospective service evaluationFrontline Gastroenterology · 2026
12. Single-Cell Transcriptomic Analysis Reveals γδ T-Cell Infiltration and Presence of Immune Regulatory Molecules in Biliary Tract Cancer MicroenvironmentAmerican Journal of Clinical Oncology · 2026
13. Persistence of Mortality-Dominant Pancreatitis Burden Despite Declining Rates, 1990–2023: An Analysis of the Global Burden of Disease 2023 StudyMedical Sciences · 2026
14. Does Parenteral Iron Increase the Risk of Infection in Patients with Gastrointestinal Cancer? A Systematic Review and Meta-AnalysisCancers · 2026
15. Recent advances in our understanding of the gut microbiome: an analysis from the Gut Microbiota for Health Expert Panel of the British Society of GastroenterologyGut · 2026
16. Role of neutropenic diet in prevention of infection and graft-versus-host disease in haematopoietic stem cell transplant recipients: systematic review and meta-analysis protocolFrontiers in Nutrition · 2026
17. Integrated Single-Cell Transcriptomics Identifies γδ T-Cell Heterogeneity and a Candidate HLA-E–NKG2A Regulatory Axis in Pancreatic Ductal AdenocarcinomaCancers · 2026
18. Burden of non-cancer comorbidities and mortality in chronic pancreatitis: a retrospective cohort studyBMJ Open Gastroenterology · 2026
19. Glucocorticoid excess disrupts NAD+ homeostasis in male and female miceJournal of Endocrinology · 2026
20. TeloNet is born: why all specialities need to be aware of telomere biology disordersFrontiers in Medicine · 2026