Centre for Structural Systems Biology

Recent papers from Centre for Structural Systems Biology

1. Global analysis of thermal and chemical denaturation using CheMelt : Thermodynamic dissection of highly thermostable de novo designed proteinsProtein Science · 2026
2. Targeting the AcrAB-TolC efflux pump by small molecules selectively addressing the outer membrane factor TolCFrontiers in Pharmacology · 2026
3. Clathrin adaptors drive phase separation in endocytosis and traffickingCommunications Biology · 2026
4. Perspectives for pharmaceutical screening at XFEL sources using the example of Lassa virus endonucleaseActa Crystallographica Section D Structural Biology · 2026
5. The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF ‐Tu for AMPylationFEBS Letters · 2026
6. Atlastin-2-mediated endoplasmic reticulum membrane tethering is critical for flavivirus replicationPLoS Biology · 2026
7. Nx3 Is a Z-Disk Structural and Signaling Hub That Is Reduced in Heart FailureCirculation Research · 2026
8. A new class of lipid transfer proteins is required for the recycling of lipids from the P. falciparum digestive vacuole2026
9. AMPK phosphorylation proceeds through hierarchical proteoform cascades revealed by integrated mass spectrometryScience Advances · 2026
10. The membrane-to-cortex distance regulates mDia1 activity to control cortical mechanicsNature Communications · 2026
11. Molecular virulence mechanism of phospholipase C from Pseudomonas aeruginosaProtein & Cell · 2026
12. In-cell discovery and characterization of a non-canonical bacterial protein translocation-folding complexCell · 2026
13. γ-Monoalkyl triphosphate analogues of acyclic nucleoside phosphonates inhibit SARS-CoV-2 replication in vitro by inducing dissociation of the minimal replication-transcription complexAntiviral Research · 2026
14. Ancestral proteins trace the emergence of substrate specificity and oligomerization within bacterial DEDDy dinucleasesScience Advances · 2026
15. Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2Nature Communications · 2026
16. RNA selectively modulates activity of virulent amyloid PSMα3 and host-defense LL-37 via phase separation and aggregation dynamicseLife · 2026
17. Current challenges in cryogenic super-resolution fluorescence microscopy in the context of cryogenic electron microscopy/tomographyCurrent Opinion in Structural Biology · 2026
18. Direct interaction of Vδ7 TCRs with IL17RA drives the differentiation of T H 1-like γδT cellsScience · 2026
19. Evolutionarily conserved short linear motifs drive actin filament bindingNature Cell Biology · 2026
20. Antibody Binding to Peptide Conjugated Gold Nanoparticles Preferring Dense Antigen Coating with Small Deflection AngleACS Nanoscience Au · 2026