Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais

Recent papers from Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais

1. Mechanisms underlying rheumatic heart disease immune-mediated pathogenesis: T-cell responses, cytokine networks, and immune dysregulation as drivers of valvular injuryThe Lancet Microbe · 2026
2. In silico discovery and serological validation of Trypanosoma cruzi-specific B-cell epitopes for high-precision Chagas disease diagnosisFrontiers in Microbiology · 2026
3. Innovative Peptide Formulations for Cardiovascular Diseases Using Supercritical CO2: A Comprehensive Review and Potential ApplicationsEuropean Journal of Pharmaceutical Sciences · 2026
4. Integrated Telehealth Rehabilitation and Quality of Life in Mechanically Ventilated AdultsJAMA · 2026
5. An observational study to test the potency of GLP-grade phenol-free lyophilised leishmanin antigen formulationEBioMedicine · 2026
6. Chemometric Tools for Optimizing an Analytical Method and Evaluating the Mineral Composition of Industrialized Fruit JuicesCurrent Analytical Chemistry · 2026
7. Predictors of mortality among individuals with advanced HIV disease in a contemporary Brazilian cohortRevista Panamericana de Salud Pública · 2026
8. Immunomodulatory and regenerative effects of human umbilical cord MSC-EVs in Cutaneous LeishmaniasisStem Cell Research & Therapy · 2025
9. Systemic Soluble and Cellular Immune Response in Acute Rheumatic Fever and Rheumatic Heart Disease: A Systematic Review of Human StudiesPathogens · 2025
10. Global Landscape of Molecular and Immunological Diagnostic Tests for Human Leishmaniasis: A Systematic Review and Meta-AnalysisPathogens · 2025
11. Annexin A1 downregulates in vitro IL-1β production in L. braziliensis-infected cellsFrontiers in Immunology · 2025
12. Topical AuNPs-Cys-Sm29 gel modulates the course of lesion development in experimental cutaneous leishmaniasisPLoS neglected tropical diseases · 2025
13. mGem: Extracellular vesicles in Leishmania —secret messengers driving infection and diseasemBio · 2025
14. Enhanced Energized Dispersive–Guided Extraction Using Doehlert Matrix Optimization and Antioxidant Evaluation of Phenolic Compounds From Herbal Leaves by Using High‐Performance Liquid ChromatographyJournal of Separation Science · 2025
15. Oral Treatment With Heat Shock Protein 65‐Producing Lactococcus lactis Induces Regulatory T Cells, Modulating Inflammatory Response in Leishmania braziliensis InfectionImmunology · 2025
16. Magnetic resonance imaging in the diagnosis of HTLV-1-associated myelopathyArquivos de Neuro-Psiquiatria · 2025
17. Single-Cell Targeted Transcriptomics Reveals Subset-Specific Immune Signatures Differentiating Asymptomatic and Cardiac Patients With Chronic Chagas DiseaseThe Journal of Infectious Diseases · 2025
18. Treatment options applied to the preclinical studies using animal models for Chagas Disease: a systematic review and meta-analysisF1000Research · 2025
19. Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunctionFrontiers in Immunology · 2025
20. Predictors of mortality among individuals with advanced HIV disease in a contemporary Brazilian cohortRevista Panamericana de Salud Pública · 2025