The Hamner Institutes for Health Sciences

Recent papers from The Hamner Institutes for Health Sciences

1. Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicityToxicology and Applied Pharmacology · 2024
2. Investigating the mode of action for wasting produced by tetrachlorodibenzo-p-dioxin (TCDD) in rats using transcriptomics: Evidence for roles of AHR and ARNT in circadian cycling2024
3. Acute cardiovascular effects of inhaled ambient particulate matter: Chemical composition-related oxidative stress, endothelin-1, blood pressure, and ST-segment changes in Wistar ratsChemosphere · 2022
4. Toxicity and occupational exposure assessment for hydroprocessed esters and fatty acids (HEFA) alternative jet fuelsJournal of Toxicology and Environmental Health · 2020
5. Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloropreneInhalation Toxicology · 2019
6. Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo ExtrapolationToxicological Sciences · 2019
7. Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessmentRegulatory Toxicology and Pharmacology · 2018
8. Time‐ and concentration‐dependent genomic responses of the rat airway to inhaled nickel sulfateEnvironmental and Molecular Mutagenesis · 2017
9. Contribution of ATM and ATR kinase pathways to p53‐mediated response in etoposide and methyl methanesulfonate induced DNA damageEnvironmental and Molecular Mutagenesis · 2017
10. The Evolution of the Ribosomal Protein–MDM2–p53 PathwayCold Spring Harbor Perspectives in Medicine · 2016
11. Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism StudiesFrontiers in Bioengineering and Biotechnology · 2016
12. Editor’s Highlight: Screening ToxCast Prioritized Chemicals forPPARGFunction in a Human Adipose-Derived Stem Cell Model of AdipogenesisToxicological Sciences · 2016
13. Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicityArchives of Toxicology · 2016
14. Editor’s Highlight: Development of anIn vitroAssay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety AssessmentToxicological Sciences · 2016
15. Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell functionScientific Reports · 2016
16. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingNature Communications · 2016
17. The Human Toxome Collaboratorium: A Shared Environment for Multi-Omic Computational Collaboration within a ConsortiumFrontiers in Pharmacology · 2016
18. Approaches for characterizing threshold dose–response relationships for DNA-damage pathways involved in carcinogenicityin vivoand micronuclei formationin vitroMutagenesis · 2016
19. Information-dependent Enrichment Analysis Reveals Time-dependent Transcriptional Regulation of the Estrogen Pathway of Toxicity2016
20. Nuclear Receptor-Mediated Gene Expression Changes in a Human Hepatic Micropatterned Coculture Model After Treatment with Hepatotoxic CompoundsApplied In Vitro Toxicology · 2016