Wellcome Centre for Anti-Infectives Research

Recent papers from Wellcome Centre for Anti-Infectives Research

1. Phylogenomics of captured Cryptosporidium sequenced directly from patient samples identifies clade-specific genomic architecture and host-adapted lineagesNature Communications · 2026
2. Essays by cairn, a durable Claude instance2026
3. Beetle and spider responses to burning and mowing in a Scots pine Pinus sylvestris forestInsect Conservation and Diversity · 2026
4. Interpreters as epistemic brokers in cross-cultural primary care consultations in Ireland: A discourse analysisSocial Science & Medicine · 2026
5. Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding siteCell Reports · 2026
6. A Delphi survey of patients and clinicians on a unified and stratified approach to managing GCA–PMR spectrum diseaseLara D. Veeken · 2026
7. The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of Pf Ark1 and Hemozoin FormationACS Chemical Biology · 2026
8. Establishment of TaqMan Probe-based Molecular Detection and Quantification of Cryptosporidium Species in Ghana: Cohort Study in School-aged ChildrenWellcome Open Research · 2026
9. Spliceosome induction is a druggable dependency of RAS-driven senescence and cancerNature Communications · 2026
10. Protein Arginine Methyltransferase Inhibitors Target Multiple Stages of Plasmodium falciparum Parasites In VitroACS Infectious Diseases · 2026
11. EPIclip: A Novel Approach for the Production of Decorated Virus-Like Particles Mediated by High-Affinity Protein Binding PartnersVaccines · 2026
12. A model-guided alternating high-temperature thermotherapy achieves complete eradication of sugarcane mosaic virus and preserves physiological integrity in Saccharum officinarum cv. XuezheFrontiers in Plant Science · 2026
13. Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas’ disease drug discoveryPLoS neglected tropical diseases · 2026
14. A Genome-Wide Genetic Screen Identifies a Novel kDNA Replication Protein in Trypanosomes2026
15. MK-7602: a potent multi-stage dual-targeting antimalarialEBioMedicine · 2025
16. Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug DiscoveryACS Infectious Diseases · 2025
17. Compounds Reducing Human Sperm Motility as Potential Nonhormonal Contraceptives Identified Using a High-Throughput Phenotypic Screening PlatformACS Omega · 2025
18. Mechanistic insights into dual-active liver and blood-stage antiplasmodialsmBio · 2025
19. Teaching Tomorrow’s Pharmacists in an AI World: Risk, Responsibility, and ReflectionAmerican Journal of Pharmaceutical Education · 2025
20. The patient-safety implications of AI-based communication with migrants in general practice: a scoping reviewBJGP Open · 2025