Michael J. Fox Foundation

Recent papers from Michael J. Fox Foundation

1. Clinical Reasoning: A 69-Year-Old Female Patient With Rapid-Onset Levodopa-Responsive Rest Tremor, Parkinsonism, and Gait FreezingNeurology · 2026
2. Path to Prevention Platform Trial in Early-Stage Neuronal Alpha-Synuclein Disease: Study Design2026
3. Statistical design of Path to Prevention platform trial in early neuronal alpha-synuclein disease2026
4. Bridge funding through a non-profit partnership to sustain disrupted neurodegenerative research and early career investigatorsnpj Parkinson s Disease · 2026
5. Rates of Phenoconversion and Progression to Functionally Meaningful Impairment in NSD Stage 2B Participants: PPMI Cohort2026
6. Considerations for therapeutic targets for clinical trials in biomarker-characterized prodromal Parkinson's disease populationsJournal of Parkinson s Disease · 2026
7. Resting state fMRI network topographies in preclinical and early Parkinson’s disease stagesnpj Parkinson s Disease · 2026
8. Modeling Framework for Economic Evaluation of Disease-Modifying Therapies in Parkinson’s Disease: Evidence Review and Expert OpinionPharmacoEconomics · 2026
9. Reciprocity in research: Participant views on return of results in the WATCH-PD qualitative studyJournal of Parkinson s Disease · 2026
10. α‐Synuclein Seeding Discriminates Between LRRK2 G2019S Variant Carriers with and Without Parkinson's DiseaseMovement Disorders · 2026
11. Cognition endpoints for Parkinson's disease: A roadmap for developing patient-focused assessment tools to accelerate drug developmentJournal of Parkinson s Disease · 2026
12. We Set Out to Break the Mold in Science Philanthropy—It’s Still Not EnoughJAMA · 2026
13. TDP-43–Associated Neurodegenerative Disease Conceptualization and Integrated StagingJAMA Neurology · 2026
14. Regulatory endorsement for the application of α-synuclein seed amplification assay as a susceptibility and risk biomarker for clinical trials targeting synucleinopathiesJournal of Parkinson s Disease · 2026
15. Crowdsourcing and machine learning contests in Parkinson's disease research - when do they work?Journal of Parkinson s Disease · 2026
16. Associations Between Cumulative Head Trauma and Self‐Reported Parkinsonism and Parkinson's Disease in Former Soccer PlayersMovement Disorders · 2026
17. Construct optimization for AAV-mediated human α-syn overexpression, and validation across research settings: Development of a shared tool for the research communityJournal of Parkinson s Disease · 2026
18. Parkinson's disease drug therapies in the clinical trial pipeline: 2015–2024Journal of Parkinson s Disease · 2026
19. Outcomes in Long‐Term Follow‐Up of Sporadic Parkinson's Disease in the Parkinson's Progression Markers InitiativeAnnals of Neurology · 2026
20. Strategic consensus on the clinical translation of advanced therapies in paediatric rare neurological disordersNeurotherapeutics · 2026