Parker Hughes Cancer Center

Recent papers from Parker Hughes Cancer Center

1. A Previously Unknown Unique Challenge for Inhibitors of SYK ATP-Binding Site: Role of SYK as A Cell Cycle Checkpoint RegulatorEBioMedicine · 2014
2. Strategy Content and Public Service Provider Performance in the Uk: An Alternative ApproachPublic Administration · 2014
3. Regulatory Phosphorylation of Ikaros by Bruton's Tyrosine KinasePLoS ONE · 2013
4. Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of IkarosProceedings of the National Academy of Sciences · 2012
5. Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A–PBX1 fusion gene expression in human Pre-B leukemiaIntegrative Biology · 2012
6. Clinical Activity of Folinic Acid in Patients with Chronic Fatigue SyndromeArzneimittelforschung · 2011
7. Therapeutic nanoparticle constructs of a JAK3 tyrosine kinase inhibitor against human B-lineage ALL cellsArzneimittelforschung · 2011
8. Recombinant human CD19‐ligand protein as a potent anti‐leukaemic agentBritish Journal of Haematology · 2011
9. Chemoprevention of Colorectal Cancer by Targeting Janus Kinase 3 With a Rationally Designed Small Molecule InhibitorNutrition and Cancer · 2010
10. CD22 EXON 12 deletion as a pathogenic mechanism of human B-precursor leukemiaProceedings of the National Academy of Sciences · 2010
11. Gene expression profiles of infant acute lymphoblastic leukaemia and its prognostically distinct subsetsBritish Journal of Haematology · 2010
12. Targeting SYK kinase‐dependent anti‐apoptotic resistance pathway in B‐lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimicBritish Journal of Haematology · 2010
13. STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stressProceedings of the National Academy of Sciences · 2010
14. Polo‐like‐kinase 1 (PLK1) as a molecular target to overcome SYK‐mediated resistance of B‐lineage acute lymphoblastic leukaemia cells to oxidative stressBritish Journal of Haematology · 2009
15. Clinical Potential of Targeting Bruton's Tyrosine KinaseInternational Reviews of Immunology · 2008
16. Ten-year survival of children with acute lymphoblastic leukemia: A report from the Children's Oncology GroupLeukemia & lymphoma/Leukemia and lymphoma · 2008
17. Targeting Mast Cells in Endometriosis with Janus Kinase 3 Inhibitor, JANEX‐1American Journal of Reproductive Immunology · 2007
18. Evaluation of local tolerance of the antiretroviral spermicide (WHI‐07)‐loaded gel‐microemulsion in the porcine female reproductive tractJournal of Applied Toxicology · 2007
19. Meta Analysis of Advanced Cancer Survival Data Using Lognormal Parametric Fitting: A Statistical Method to Identify Effective Treatment ProtocolsCurrent Pharmaceutical Design · 2007
20. Limitations of the Human‐PBL‐SCID Mouse Model for Vaginal Transmission of HIV‐1American Journal of Reproductive Immunology · 2007