Collaborations Pharmaceuticals (United States)

Recent papers from Collaborations Pharmaceuticals (United States)

1. Uncertainty Quantificationwith Domain ClassificationModels for Acetylcholinesterase InhibitionJournal of Chemical Information and Modeling · 2026
2. Efficacy, Structure–Activity Relationship, and Mode of Action Studies of a New Generation of Acridine/Acridone-Based AntimalarialsACS Infectious Diseases · 2026
3. Repurposing Clinical Candidates for Nipah and Hendra Viruses.2026
4. Enhanced Antiviral Activity of Novel Umifenovir Derivatives against SARS-CoV-2: Insights from an International Collaborative StudyACS Omega · 2026
5. Annus Horribilis—Challenging the Attacks on Science and Funding in the USAGEN Biotechnology · 2026
6. Human CYP2C9 Metabolism of Organophosphorus Pesticides and Nerve Agent SurrogatesJournal of Xenobiotics · 2025
7. Machine learning modeling of zebrafish toxicity endpoints after exposure to PROTACsToxicological Sciences · 2025
8. New Insights into Batten Disease CLN1 from a Patient Facing Registry2025
9. MegaEye: Applying multiple machine learning approaches to identify oral compounds with ocular bioactivityArtificial Intelligence in the Life Sciences · 2025
10. Repurposing nicardipine leads to improved development in a young patient with Pitt–Hopkins syndromeFrontiers in Pharmacology · 2025
11. DDI-CYP: Metabolism Ensemble Models for Drug-Drug Interaction PredictionsDrug Metabolism and Disposition · 2025
12. ToxPoint: The case for Equilibrative Nucleoside Transporters in current regulatory guidanceToxicological Sciences · 2025
13. De-risking seizure liability: integrating adverse outcome pathways (AOPs), new approach methodologies (NAMs), and in silico approaches while highlighting knowledge gapsToxicological Sciences · 2025
14. Machine Learning and Large Language Models for Modeling Complex Toxicity Pathways and Predicting SteroidogenesisEnvironmental Science & Technology · 2025
15. Applications of artificial intelligence in drug discovery for neurological diseasesNeurotherapeutics · 2025
16. Adverse Outcome Pathway and Machine Learning to Predict Drug Induced Seizure LiabilityACS Chemical Neuroscience · 2025
17. Development and Characterization of pFluor50, a Fluorogenic-Based Kinetic Assay System for High-Throughput Inhibition Screening and Characterization of Time-Dependent Inhibition and Inhibition Type for Six Human CYPsMolecules · 2025
18. Cryo-EM Structure of HIV-1 Reverse Transcriptase with N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside InhibitorACS Infectious Diseases · 2025
19. Repurposing a Combination of Palbociclib and Afatinib Halts Chordoma Growth in a Mouse ModelGEN Biotechnology · 2025
20. Computational Approaches for Predicting Drug Interactions with Human Organic Anion Transporter 4 (OAT4)Molecular Pharmaceutics · 2025