Target (Germany)

Recent papers from Target (Germany)

1. Mammals produce cyclo -octasulfur to suppress lipid peroxidation and ferroptosisScience · 2026
2. Intracellular complement factor H protects neurons during CNS inflammationNature · 2026
3. PA200 modulates immunoproteasome structure and activityNature Communications · 2026
4. SpotMAX: A generalist framework for multidimensional automatic spot detection and quantificationScience Advances · 2026
5. A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcriptionCell Reports · 2026
6. Caspase-3/7 deficiency results in enhanced intestinal inflammation and reduced tumorigenesisScience Advances · 2026
7. A beneficial environment promotes immune resilience through epigenetic regulationScience Advances · 2026
8. Evolutionary remodeling of a remnant GET pathway factor into PEX38, an essential peroxinProceedings of the National Academy of Sciences · 2026
9. Local mitochondrial physiology defined by mtDNA quality guides purifying selectionPLoS Genetics · 2026
10. A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosisCell · 2025
11. Targeting FSP1 triggers ferroptosis in lung cancerNature · 2025
12. Lymph node environment drives FSP1 targetability in metastasizing melanomaNature · 2025
13. Conformational Quenching in an Engineered Lipocalin Protein Achieves High Affinity Binding to the Toxin ColchicineAngewandte Chemie · 2025
14. Structural perspective on the design of selective DYRK1B inhibitorsInternational Journal of Biological Macromolecules · 2025
15. Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line modelsCommunications Medicine · 2025
16. NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivoThe EMBO Journal · 2025
17. Exploring the omnigenic architecture of selected complex traitsThe American Journal of Human Genetics · 2025
18. Genotype-Phenotype Correlation in RBM10-Associated Syndromes – How Variant Function Shapes a Broad Phenotypic Landscape2025
19. Deciphering the RNA recognition by Musashi-1 to design protein and RNA variants for in vitro and in vivo applicationsNucleic Acids Research · 2025
20. Inter-domain flexibility and AI-guided sequence optimization enhance de novo enzyme function2025