Centre for Drug Research and Development

Recent papers from Centre for Drug Research and Development

1. Discovery of a Novel HDAC1 Inhibitor to Potentiate Ferroptosis with Arachidonic Acid in ESCCJournal of Medicinal Chemistry · 2026
2. The rise and fall of TRPV1-targeted analgesia in osteoarthritis: a critical appraisalExpert Opinion on Pharmacotherapy · 2026
3. Lévy Formulation of the Stochastic Theory of Chromatography and Extension to Phase-Type Markov Renewal ProcessAnalytical Chemistry · 2026
4. Regulation on the rocks: Community-directed appraisal on the projected harms of reform to alcohol pricing in the Downtown Eastside of VancouverInternational Journal of Drug Policy · 2026
5. MexXY-OprM efflux pump mediates resistance to odilorhabdins in Pseudomonas aeruginosaMicrobiology Spectrum · 2026
6. Comparative evaluation for small molecule somatostatin 4 receptor agonists: in silico, in vitro, and in vivo approachesFrontiers in Pharmacology · 2026
7. Rapid N -Trifluoromethylsulfinylation of Sulfoximines in Batch and FlowThe Journal of Organic Chemistry · 2026
8. Difluorocarbene-Enabled Selective Cleavage and Reconstruction of Aliphatic Tertiary Amine C sp ³ –N BondsOrganic Letters · 2026
9. Formal [2 + 2 + 1 + 1] Annulation Enabled Synthesis and Anti-inflammatory Evaluation of Dimeric TetrahydroisoquinolinesOrganic Letters · 2026
10. The sigma-1 receptor agonist fluvoxamine alleviates endotoxin-induced acute lung injury in miceSHILAP Revista de lepidopterología · 2026
11. Structure-Based Optimization of Triazole-Linked Sesamol Conjugates as Antifungal Agents Targeting CYP51 in Candida albicansACS Infectious Diseases · 2026
12. Kinetic Study of Metalloporphyrin-Based Biomimetic Oxidation of Drugs Using One-Shot and Continuous Oxidizing Agent Addition ModesThe Journal of Physical Chemistry B · 2026
13. Inside Front Cover: Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide ReplicationAngewandte Chemie International Edition · 2026
14. Oscillation-generating micromixing (FDmiX) – a new method for manufacturing of mRNA-lipid nanoparticles with scalable high-throughput productionJournal of Controlled Release · 2026
15. Biotransformation of Allium Sulfur Metabolites by Proteus mirabilis Yields Cepathiosoxide, a Trithiabicyclic SulfoxideOrganic Letters · 2026
16. Journey of Methionine Adenosyltransferase 2A Inhibitors: From Bench to Advanced Clinical TrialsJournal of Medicinal Chemistry · 2026
17. Strain-Release-Driven [4 + 1] Annulation: Leveraging Bicyclo[1.1.0]butanes as C1 Synthons via Rh(III) CarbenoidACS Catalysis · 2026
18. Hydrogen Bonding as a Failure Mechanism for Release of Ibuprofen-Copovidone Amorphous Solid DispersionsMolecular Pharmaceutics · 2026
19. Confiscations, public health obstructions, and perpetual displacement: Experiences and perspectives on urban law enforcement practices during a period of “recriminalization” among people who use criminalized drugsInternational Journal of Drug Policy · 2026
20. Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide ReplicationAngewandte Chemie International Edition · 2026