MedSIR (Spain)

Recent papers from MedSIR (Spain)

1. 5-year outcomes of chemotherapy de-escalation in HER2-positive early breast cancer and exploratory circulating tumor DNA analyses from the randomized phase 2 PHERGain trialNature Medicine · 2026
2. Germline pharmacogenetic variants associated with trastuzumab deruxtecan-induced interstitial lung disease in advanced breast cancer: PROCURE projectESMO Open · 2026
3. Talazoparib plus enzalutamide in high-volume metastatic hormone-naive prostate cancer: a randomized phase 2 trialNature Medicine · 2026
4. Cerebrospinal fluid and plasma circulating tumor DNA dynamics as a biomarker of response during trastuzumab deruxtecan treatment in patients with breast cancer with leptomeningeal diseaseClinical Cancer Research · 2026
5. Artificial intelligence for clinical data extraction from EHRs in breast cancer trials: the MIRROR studynpj Breast Cancer · 2026
6. Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLCNature Medicine · 2026
7. Low Rates of Discontinuation Unrelated to Disease Progression with Trastuzumab Deruxtecan in Metastatic Breast Cancer: A Real-World StudyCancers · 2026
8. Navigating uncertainties and evidence gaps in adjuvant therapy for premenopausal women with HR+/HER2- breast cancerAnnals of Oncology · 2026
9. Microsatellite instability in penile cancer: comparative analysis of primary tumors and metastasesFrontiers in Urology · 2026
10. Targeted therapies for psoriasis and atopic dermatitis in the context of malignancy: SPIN ‐ FRT recommendationsJournal of the European Academy of Dermatology and Venereology · 2026
11. HER2DX in early-stage HER2-positive breast cancer: a review of clinical utilityESMO Open · 2026
12. Identification of key symptoms impacting HRQOL in advanced renal cell carcinoma: nivolumab plus cabozantinib versus sunitinib in CheckMate 9ERThe Oncologist · 2026
13. An individualized patient decision-making tool to improve decision making in non-small cell lung cancer: a mixed methods approachESMO Real World Data and Digital Oncology · 2026
14. Circulating tumor DNA in early breast cancer: Evidence, challenges, next stepsCancer · 2026
15. Serious mental illness and cancer: A call to action for equitable careCA A Cancer Journal for Clinicians · 2026
16. Association of BMI With Efficacy and Safety of Abemaciclib in Patients With Breast Cancer Treated in the monarchE TrialJCO oncology advances. · 2026
17. Metabolic determinants of cancer immunotherapy outcomes identified by plasma profilingNature Medicine · 2026
18. Pan-cancer multi-omic integration of Trop2 reveals biological determinants and translational implications for ADC therapynpj Precision Oncology · 2026
19. SERENA-6 interpretation and clinical implications: intercepting endocrine resistance in metastatic breast cancernpj Breast Cancer · 2026
20. Treatment of ALK+ Non–Small Cell Lung Cancer in the Brazilian Public and Private Health Care Systems: A Tale of Inequalities (LACOG/GBOT 1918)JCO Global Oncology · 2026