Harvard NeuroDiscovery Center

Recent papers from Harvard NeuroDiscovery Center

1. APOE Isoform-Dependent Self-Association Measured by a Split-Luciferase Complementation Assay: Differential Effects of Disease-Risk and Protective Variants2026
2. Postpartum adversity in rats creates a hypervigilant maternal state through selective salience-circuit recruitmentNeurobiology of Stress · 2026
3. APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer diseaseMolecular Therapy · 2024
4. APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease2023
5. Heparin interferes with the uptake of liposomes in gliomaInternational Journal of Pharmaceutics X · 2023
6. Megakaryocytes respond during sepsis and display innate immune cell behaviorsFrontiers in Immunology · 2023
7. Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT NetworkAmerican Journal Of Pathology · 2023
8. GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer’s DiseaseFrontiers in Cellular Neuroscience · 2022
9. Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson’s diseaseMolecular Neurodegeneration · 2022
10. APOE4 derived from astrocytes leads to blood–brain barrier impairmentBrain · 2021
11. Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in miceScience Translational Medicine · 2021
12. Transcriptomic Analysis of Laser Capture Microdissected Tumors Reveals Cancer- and Stromal-Specific Molecular Subtypes of Pancreatic Ductal AdenocarcinomaClinical Cancer Research · 2021
13. Comparative Analysis Identifies Similarities between the Human and Murine Microglial SensomesSHILAP Revista de lepidopterología · 2021
14. Orally Administered 5-aminolevulinic Acid for Isolation and Characterization of Circulating Tumor-Derived Extracellular Vesicles in Glioblastoma PatientsCancers · 2020
15. Kymolyzer, a Semi‐Autonomous Kymography Tool to Analyze Intracellular MotilityCurrent Protocols in Cell Biology · 2020
16. Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsisScientific Reports · 2020
17. Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21Cell Reports · 2019
18. Megakaryocytes Display Innate Immune Cell Functions and Respond during Sepsis2019
19. Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1Molecular Therapy — Methods & Clinical Development · 2019
20. A New Test for the Detection of Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in the Emergency Room SettingCritical Care Explorations · 2019