WuXi AppTec (United States)

Recent papers from WuXi AppTec (United States)

1. Small interfering RNA targeting protein Z-dependent protease inhibitor improves hemostasis in Von Willebrand factor- and Factor X-deficient miceThrombosis and Haemostasis · 2026
2. Construction of Quinoline-4-carboxylic Acids via DNA-Compatible Doebner ReactionOrganic Letters · 2026
3. An artificial intelligence–driven workflow to detect the macula and quantify retinal ganglion cells in nonhuman primatesVeterinary Pathology · 2026
4. Abstract 4804: Synchronously implanted cold tumor abrogates anti-PD-1 response of hot tumor in a syngeneic mouse modelCancer Research · 2026
5. Systematic Evaluation of Electrophile Reactivity and Stability for Covalent DNA‐Encoded LibrariesHelvetica Chimica Acta · 2026
6. Development and validation of an ultra-sensitive UPLC-MS/MS method for quantification of monomethyl auristatin E in cynomolgus monkey plasma: application to pharmacokinetic studyBioanalysis · 2026
7. Defect-Topology Control of Anisotropic Lattice Flexibility for High-Performance Fluoride-Ion Electrolytes2026
8. Accelerating the pace and accuracy of systematic reviews using AI: a validation studySystematic Reviews · 2025
9. Application of acoustic ejection mass spectrometry for plasma protein binding assay using flux dialysisDrug Metabolism and Disposition · 2025
10. Van Leusen Imidazole Synthesis for One-Bead-One-Compound DNA-Encoded LibrariesBioconjugate Chemistry · 2025
11. An LC–MS/MS Assay of Irsenontrine, a Novel Phosphodiesterase-9 Inhibitor, in Human Plasma, Urine and Cerebrospinal Fluid for Application to Clinical Pharmacokinetic StudiesACS Omega · 2025
12. Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern valuesFrontiers in Toxicology · 2025
13. Self-silencing adenovirus enables precise infectious titration of recombinant adeno-associated viral vectorsMolecular Therapy — Methods & Clinical Development · 2025
14. CuOTf(Tol)1/2-Catalyzed O-Trifluoroethylation of Alcohols with 2,2,2-TrifluorodiazoethaneOrganic Letters · 2025
15. Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)2025
16. Development and validation of an ultrasensitive qPCR method to identify and quantify EGFR T790M in cell-free DNABioanalysis · 2025
17. Characterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modelingJournal of Pharmaceutical Analysis · 2024
18. Development of a DNA-encoded library screening method “DEL Zipper” to empower the study of RNA-targeted chemical matterSLAS DISCOVERY · 2024
19. Inactivation of bacteria using synergistic hydrogen peroxide with split-dose nanosecond pulsed electric field exposuresPLoS ONE · 2024
20. Effects of Message Frames and Sources in TikTok Videos for Youth Vaping Cessation: Emotions and Perceived Message Effectiveness as Mediating MechanismsJournal of Adolescent Health · 2024