Purdue University Institute for Cancer Research

Recent papers from Purdue University Institute for Cancer Research

1. Tuning the immune ecosystem to treat cancerScience · 2026
2. Radiation-induced transient metabolic rewiring uncovers a glutamine transport therapeutic vulnerability in triple-negative breast cancerBreast Cancer Research · 2026
3. Identification, optimisation, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for ubiquitin C-terminal Hydrolase L3Journal of Enzyme Inhibition and Medicinal Chemistry · 2026
4. Decoding Emerging Protein Post-Translational Modifications Through Chemical BiologyProteomes · 2026
5. Targeting Cardiac Fibrosis with Chimeric Antigen Receptor Neutrophils Derived from Human Pluripotent Stem Cells2026
6. TIM ‐3 Functions as an Activator of NK Cells in GBM and Can Be Upregulated by Torin‐1: Implications for Exogenous NK Cell TransplantationImmunology · 2026
7. An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilienceNature Neuroscience · 2026
8. Comprehensive multi-omics analysis identifies BTG2 as a potential regulator of radiotherapy response in lung adenocarcinomaNeoplasia · 2026
9. Magnetically Actuated Microrobot for Drug Delivery: Current Progress and ChallengesAdvanced Robotics Research · 2026
10. The Same, but Different: Shared Hallmarks and Divergent Drivers in Adult, Pediatric and Canine GliomaCurrent Oncology · 2026
11. Structural and genetic dissection of RNA-guided gene repression by TnpB-derived transcription factors2026
12. Tau-induced increase in promoter-proximal RNA polymerase II pausing is linked to suppressed expression of long neuronal genes in a Drosophila tauopathy modelFrontiers in Aging Neuroscience · 2026
13. Care Delivery in Gastrointestinal Malignancies: Disparities, Barriers, and Equity-Focused SolutionsInternational Journal of Cancer Care and Delivery · 2026
14. Cryo-EM structure-based discovery of etravirine as a specific inhibitor of PRMT5/pICln protein-protein interaction for prostate cancer treatmentJournal of Enzyme Inhibition and Medicinal Chemistry · 2026
15. Single-nucleus transcriptomics reveals disrupted pathways in the prefrontal cortex of Scn2a-deficient miceTranslational Psychiatry · 2026
16. Proteomic Signatures of Vemurafenib Resistance in Canine Urothelial Carcinoma Harboring the BRAF V595E MutationJournal of Proteome Research · 2026
17. High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small MoleculesAnalytical Chemistry · 2026
18. Early-stage drug discovery in a new-generation ultrahigh-throughput mass spectrometry platformProceedings of the National Academy of Sciences · 2026
19. SLC1A5 augmentation bypasses NK cell transduction barriers to deliver complex CAR payloadsThe Journal of Immunology · 2026
20. Effects of different mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance.2026