Chan Zuckerberg Biohub San Francisco

Recent papers from Chan Zuckerberg Biohub San Francisco

1. A Compact Regulatory Logic Governs Fibroblast Cell State Plasticity in Fibrosis2026
2. A single-cell atlas of human neutrophils reveals neutrophil heterogeneity across health and diseaseNature Immunology · 2026
3. “Locking” CDK9 inhibition by activating integrator function in HIV transcriptioniScience · 2026
4. Identification of regulators of aryl hydrocarbon receptor signaling in human cells by genome-scale CRISPR screeningGenome biology · 2026
5. Enhancer binding kinetics explain transcription factor hub formationScience Advances · 2026
6. PrimerDesigner: Designing Efficient Primers for Synthesizing Large Protein Libraries Without Cross-HybridizationJournal of Computational Biology · 2026
7. Prehistoric global migration of vanishing gut microbes with humansNature · 2026
8. A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast EnucleationAmerican Journal of Hematology · 2026
9. Tall adhesions overcome cell surface steric interference and rescue antibody-dependent phagocytosis in macrophagesNature Communications · 2026
10. Nucleosome Core Allostery Governs Chromatin Recognition and Cell Fate2026
11. Effects of Chemical Fixation on Stimulated Raman Scattering MicroscopyAnalytical Chemistry · 2026
12. A tripartite mechanism licenses RNA polymerase import into the phage nucleus2026
13. Extracting interpretable single-cell metabolic states with graph-guided representation learning2026
14. Machine learning reveals sequence and genomic context features underlying Alu -specific effects on genome folding2026
15. Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cellsScience Advances · 2026
16. Cardiomyocyte vulnerability to lamin polymer disruption revealed by saturation mutagenesis2026
17. Active learning enables evolutionary discovery and characterization of fungal transcriptional activatorsGenome biology · 2026
18. Benchmarking three simple DNA staining-based image metrics for live-cell tracking of chromatin organizationNucleus · 2026
19. Circulating cholesterol fuels SARS-CoV-2 replication via ORF3aEMBO Reports · 2026
20. Distinct cell states define larval and adult body plans in a hemichordateNature Communications · 2026