Vaccine and Gene Therapy Institute

Recent papers from Vaccine and Gene Therapy Institute

1. From aerosol to alveoli: materials, methods, and models to bridge barriers to respiratory delivery of RNAFrontiers in Immunology · 2026
2. Mucosal ACP subunit vaccine formulated with a small molecule STING agonist drives protective TH1/TH17 responses and serum bactericidal antibodies against Neisseria gonorrhoeae2026
3. A broadly active flavivirus NS4B targeting compound that blocks NS4B-NS3 binding and replication organelle formation2026
4. SIV reservoir depletion and clearance from neonatal macaques following transient CCR5 depletionNature Microbiology · 2026
5. Safety of Autologous Infusion of CER T Cells in Nonhuman PrimatesAIDS Research and Human Retroviruses · 2026
6. Distinct phases of immune system programming during ART-suppressed immunodeficiency virus infectionCell Reports · 2026
7. BCG vaccination at birth shapes the TCR usage and functional gene expression profile of MR1T cells at 9 weeks of ageScientific Reports · 2026
8. New horizons in HIV neuropathogenesis: thinking beyond the brainCurrent Opinion in HIV and AIDS · 2026
9. Identification of cross-stage, cross-species malaria CD8+ T cell antigensNature · 2026
10. Inhibition of type I interferon signaling is a conserved function of gamma-herpesvirus-encoded microRNAsJournal of Virology · 2025
11. Restructuring Antiviral Quinazolinone Frameworks to Derive and Optimize Inhibitors of Chikungunya VirusACS Medicinal Chemistry Letters · 2025
12. Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral ActivityACS Infectious Diseases · 2025
13. Prophylactic and therapeutic neutralizing monoclonal antibody treatment prevents lethal yellow fever infectionJCI Insight · 2025
14. Liver biopsies obtained throughout SIV infection reveal evolving interferon stimulated protein expression within distinct monocyte/macrophage subsets2025
15. Human Neonatal MR1T Cells Have Diverse TCR Usage, are Less Cytotoxic and are Unable to Respond to Many Common Childhood Pathogens2025
16. Virus-against-virus dominant-negative interference strategy targeting a viral CC chemokine prevents cytomegalovirus-related neurodevelopmental pathogenesis2025
17. Impact of Dolutegravir Plus Lamivudine as First-line Antiretroviral Treatment on the Human Immunodeficiency Virus Type 1 Reservoir and Inflammatory Markers in Peripheral BloodThe Journal of Infectious Diseases · 2024
18. Maternal Western-style diet remodels the transcriptional landscape of fetal hematopoietic stem and progenitor cells in rhesus macaquesStem Cell Reports · 2022
19. Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaquesPLoS Pathogens · 2022
20. Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus–infected rhesus macaques on antiretroviral therapyJournal of Clinical Investigation · 2022