Roche (Denmark)

Recent papers from Roche (Denmark)

1. Real-world Motor Function Outcomes with Risdiplam in Types 2 and 3 Spinal Muscular Atrophy (SMA): A Systematic Literature Review and Meta-analysis (P5-9.002)Neurology · 2026
2. Self-regulating the use of large language models in clinical practice: a risk-stratified approachBMJ Health & Care Informatics · 2026
3. Facilitating the Implementation of Physician‐Led Medication Reviews for Patients With Severe Mental Disorder and Diabetes: A Cost‐Minimization AnalysisBasic & Clinical Pharmacology & Toxicology · 2025
4. Total costs of different lines of treatment in diffuse large B-cell lymphoma in Denmark – a real-world data analysisThe European Journal of Health Economics · 2025
5. The art of sharing: From research to outreach in the social media eraExperimental Physiology · 2025
6. A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activityNature Communications · 2025
7. Therapeutically targeting the classical complement pathway with antisense oligonucleotides in Alzheimer′s disease2024
8. Does spinal pain management account for the presence of other health conditions? – A scoping reviewEuropean Journal of Physiotherapy · 2024
9. Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohortFrontiers in Molecular Biosciences · 2023
10. TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse modelsiScience · 2023
11. Peptide Conjugates of a 2′-O-Methoxyethyl Phosphorothioate Splice-Switching Oligonucleotide Show Increased Entrapment in EndosomesACS Omega · 2023
12. Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complicationsNature Cardiovascular Research · 2023
13. Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injectionMolecular Therapy — Nucleic Acids · 2023
14. Propensities of Fatty Acid-Modified ASOs: Self-Assembly vs Albumin BindingBioconjugate Chemistry · 2023
15. Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet SyndromeeNeuro · 2022
16. Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathiesMolecular Therapy — Nucleic Acids · 2022
17. Biopredictive capability assessment of two dissolution/permeation assays, µFLUX™ and PermeaLoop™, using supersaturating formulations of PosaconazoleEuropean Journal of Pharmaceutical Sciences · 2022
18. Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmersMolecular Therapy — Nucleic Acids · 2022
19. Angelman syndrome patient neuron screen identifies a potent and selective clinical ASO targeting UBE3A-ATS with long lasting effect in cynomolgus monkey2022
20. Cost of illness of HER2-positive and metastatic and recurrent HER2-positive breast cancer – a Danish register-based study from 2005 to 2016BMC Health Services Research · 2022