Pharmaron (United Kingdom)

Recent papers from Pharmaron (United Kingdom)

1. Study on Chenopodiastrum hybridum’s Anti-inflammatory and Antioxidant Effects in Zebrafish: Mechanism Against Ovarian CancerPlanta Medica · 2026
2. Discovery of Potent, Orally Bioavailable, and CNS-Penetrant 1,2,3-Triazolopyridinyl Piperazine-Based PARP1-Selective InhibitorsJournal of Medicinal Chemistry · 2026
3. Synthetic Development and Scale-Up of the Aminoindazole Fragment of LenacapavirOrganic Process Research & Development · 2026
4. Catalytic Deamino-Diels–Alder and Formal [2+2+2] Annulation Enabled by Indolyl-Vinyl-Iminium as a C4 Synthon: Divergent Assembly of Indole Polycyclic SkeletonsOrganic Letters · 2026
5. Impact of renal impairment on pharmacokinetics, safety, and tolerability of funobactam, combined with imipenem and cilastatinAntimicrobial Agents and Chemotherapy · 2026
6. On-DNA Radical Iodosulfonylation of Alkynes: Access to Bifunctional Covalent Warheads and Modular ScaffoldsOrganic Letters · 2026
7. Stereoselective Synthesis of MK-8527 Enabled by a Dynamic Kinetic Resolution Mitsunobu GlycosylationOrganic Letters · 2026
8. Discovery ofa Novel P2X2/3 Allosteric Antagonistas an Efficient Bitter Taste BlockerJournal of Medicinal Chemistry · 2026
9. 18 th GCC Closed Forum: Compliance with FDA Biomarkers Guidance, Novel ELN/LIMS Platforms, Sample Reconciliation, Emerging Technologies, Improvements in ELISpot, Post-extraction Sample Stability, LBA Singlicate, Regulatory Inspections, Chicken anti-Human IgG, Cross-validation HarmonizationBioanalysis · 2026
10. A Quantitative Efflux Ratio-Integrated Model for Passive PermeabilityEstimation from Caco-2 AssaysDrug Metabolism and Bioanalysis · 2026
11. Lung Function in Young, Active Duty U.S. Marines After SARS-CoV-2 Infection.2026
12. Development of a Phase 1 Cryptosporidiosis Controlled Human Challenge Model in Healthy Volunteers Using Current Good Manufacturing Practice Cryptosporidium Parvum Oocysts and Conducted Under an Investigational New Drug ApplicationThe Journal of Infectious Diseases · 2026
13. Diastereomer separation of phosphorothioate oligonucleotides via conformationally stabilizing ion pairs in reversed-phase liquid chromatographyJournal of Chromatography A · 2026
14. Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical EvaluationJournal of Medicinal Chemistry · 2026
15. Integration of tailored Co3O4@G with porous biochars for efficient degradation of tetracyclineFrontiers in Environmental Science · 2026
16. Mineralocorticoid Receptor Antagonists With an Acylurea as a Key Polar Interaction Motif.2026
17. Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders.2026
18. Enantioselective Suzuki–Miyaura Chemistry: Route Evolution for the Synthesis of PKMYT1 Inhibitor XL495The Journal of Organic Chemistry · 2026
19. Abstract 744: In vitro and in vivo evaluation of the bystander-killing effect of ADCs.Cancer Research · 2026
20. Safety and Immunogenicity of a Trivalent Salmonella Conjugate Vaccine to S. Typhi, S. Typhimurium, and S. EnteritidisThe Journal of Infectious Diseases · 2026